Methods and Guidelines
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Methods and Guidelines
Quality Assessment Tools Project
July 26, 2012
The Quality Assessment Tools (QAT) project identifies the most appropriate tools for evaluating and grading evidence. It is a systematic approach to identify the most appropriate quality assessment instruments for systematic reviews, randomized controlled trials and observational studies (mainl...
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Methods and Guidelines
Addendum to the Canadian Agency for Drugs and Technologies in Health Guidelines for the Economic Evaluation of Health Technologies: Specific Guidance for Oncology Products
December 22, 2009
This addendum to CADTH’s Guidelines for the Economic Evaluation of Health Technologies (3rd Edition) is intended to provide specific guidance on the methods used to conduct high-quality economic evaluations of oncology products. The oncology-specific guidelines should be considered a comp...
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Methods and Guidelines
Development and Testing of Search Filters to Identify Economic Evaluations in MEDLINE and EMBASE
October 30, 2009
Health care decision-makers and health care professionals need efficient access to the best evidence. Health technology assessment agencies and guideline developers need access to evidence from economic evaluations to identify the cost-effectiveness of a technology and to inform economic models....
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Methods and Guidelines
Using Canadian Administrative Databases to Derive Economic Data for Health Technology Assessments
March 24, 2009
A database is a compilation of information on characteristics and events that is stored in an organized manner. An administrative database in health care meets specific criteria: at least one administrative operation must use the data and consider the database to be essential; the organization that ...
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Methods and Guidelines
Indirect Evidence: Indirect Treatment Comparisons in Meta-Analysis
March 19, 2009
CADTH’s report identified and reviewed different methods available for making indirect treatment comparisons when conducting assessments of drugs and technologies. As a companion to the report, a user-friendly application for conducting indirect treatment comparisons was developed. Report Th...
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Methods and Guidelines
English-Language Restriction When Conducting Systematic Review-based Meta-analyses: Systematic Review of Published Studies
February 24, 2009
The English language is generally perceived to be the universal language of science.1,2 The top 10 international medical journals in 11 medical specialties (measured by impact factor) are English-language publications.3 The exclusive reliance, however, on data that are published in English and that ...
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Methods and Guidelines
Caveats in the Meta-Analyses of Continuous Data: A Simulation Study
March 26, 2008
INTRODUCTION Certain outcomes (e.g., blood pressure, blood glucose levels, hemoglobin, and height) are expressed as continuous data. These outcomes are reported by study investigators either as final (end-of-treatment) values or as change (change-from-baseline) values. When performing meta-analys...
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Methods and Guidelines
PRESS: Peer Review of Electronic Search Strategies
January 14, 2008
The quality of health technology assessment (HTA) reports depends on many factors. One of these factors is the evidence base from which the HTA is derived. The evidence base is created by gathering information from many sources and performing literature searches. Performing a high quality search of ...
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Methods and Guidelines
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Methods and Guidelines
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Methods and Guidelines
A national list of provincial costs for health care: Canada 1997/8
July 10, 2000
Cite as: Jacobs, P., Bachynsky, J., Hall, E. A Manual of Standard Costs for Pharmaco-Economic Studies in Canada: Feasibility Study. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1995. The purpose of this project is to determine wh...
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Methods and Guidelines
Guidelines for economic evaluation of pharmaceuticals: Canada 2nd edition
January 1, 1997
Cite as: Guidelines for economic evaluation of pharmaceuticals: Canada. 2nd. edition. Ottawa: The Canadian Coordinating Office for Health Technology Assessment; 1997. Pharmacoeconomics is the application of the methods of economic evaluation of health care programs to ...
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Methods and Guidelines
A guidance document for the costing process
January 1, 1996
Cite as: Baladi J-F. A guidance document for the cost process.Version 1.0 Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1996. This document is intended to help researchers determine costs when undertaking economic e...