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Acetylsalicylic Acid for Primary Prevention of Cardiovascular Events: Clinical Effectiveness and Guidelines

Last updated: August 19, 2019
Project Number: RB1368-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness for the use of acetylsalicylic acid in primary prevention of cardiovascular disease?
  2. What are the evidence-based guidelines for the use of acetylsalicylic acid in primary prevention of cardiovascular disease?

Key Message

Twenty-two systematic reviews and meta-analyses, eight randomized controlled trials, and eleven non-randomized studies were identified regarding the clinical effectiveness of acetylsalicylic acid in primary prevention of cardiovascular disease. Three evidence-based guidelines were identified regarding the use of acetylsalicylic acid in primary prevention of cardiovascular disease.