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Combination Atypical Antipsychotics in Adolescents or Adults with Bipolar Disorder with Psychotic Features: A Review of Clinical and Cost-Effectiveness and Guidelines

Last updated: September 6, 2016
Project Number: RC0806-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary with Critical Appraisal
Result type: Report

Question

  1. What is the clinical effectiveness of combination atypical antipsychotics in adolescent or adult patients with bipolar disorder with psychotic features?
  2. What is the cost-effectiveness of combination atypical antipsychotics in adolescent or adult patients with bipolar disorder with psychotic features?
  3. What are the evidence-based guidelines associated with the use of combination atypical antipsychotics in adolescent or adult patients with bipolar disorder with psychotic features?

Key Message

No relevant literature was identified pertaining to the clinical or cost effectiveness of combination treatment of any atypical antipsychotics in adolescents and adults suffering from bipolar disorder with psychotic features. Similarly, no evidence-based guidelines were identified from the literature search