COVID-19 Update

( Last Updated : February 22, 2021)
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CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.


Ivermectin for the Treatment and Prevention of COVID-19

  • To find effective treatment for COVID-19, researchers have started studying older drugs approved for other infections or diseases. One recent drug of interest is ivermectin, a drug typically used to treat patients with parasitic infections (e.g., roundworm).
  • This report looks at the evidence regarding ivermectin to treat patients with COVID-19 infections.
  • While some lab studies have shown ivermectin to be a promising treatment, it’s hard to know how well ivermectin works in patients because the included studies were not done well (i.e., they were of low quality). This report did not find any evidence on cost-effectiveness or any relevant guidelines.

Respiratory Personal Protective Equipment for Female Presenting Individuals

  • CADTH conducted a Rapid Response Report to search for clinical evidence or evidence-based guidelines regarding the use of respiratory personal protective equipment designed specifically for female presenting individuals during COVID-19.
  • However, no clinical evidence or evidence-based guidelines were identified. References that did not meet the inclusion criteria, but may still be of interest, were included in the Appendix.

Remdesivir: Evidence Review and Appraisal

  • CADTH updated a Health Technology Review on remdesivir — an antiviral drug currently being used to treat COVID-19.
  • Remdesivir was approved in Canada on July 27, 2020 to treat adults and adolescents with severe symptoms of COVID-19 who have pneumonia and require extra oxygen.
  • The update includes the addition of interim study results of WHO Solidarity trial.

COVID-19 News

Visit our COVID-19 news page to stay on top of all the emerging information we are monitoring and updating.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:


Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.