CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.
Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.
The following is a summary of the most recent information posted to our COVID-19 portal.
- This report (last updated on April 23, 2021) reviews the current scientific evidence on the potential benefits and harms of chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19.
- The current evidence does not support the use of high-dose chloroquine because of concerns of cardiac toxicity and increased lethality relative to low-dose chloroquine.
- The results of the included studies also do not support the use of hydroxychloroquine for treating patients with mild, moderate, or severe COVID-19, nor does hydroxychloroquine appear to prevent COVID-19 post-exposure.
Visit our COVID-19 news page to stay on top of all the emerging information we are monitoring and updating.
CADTH Literature Searching Tools
CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:
CAN’T FIND WHAT YOU NEED? LET US KNOW
Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.
The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal.