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Decreased Dosing of Bacillus Calmette-Guérin for Bladder Cancer: Clinical Effectiveness, Safety, and Guidelines

Last updated: September 24, 2014
Project Number: RA0701-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report

Question

  1. What is the clinical effectiveness and safety of using one-third of the recommended dose of bacillus Calmette-Guérin for the treatment of adult patients with bladder cancer?
  2. What are the evidence-based guidelines regarding the reconstitution of bacillus Calmette-Guérin?

Key Message

Three randomized controlled trials, one non-randomized study, and one evidence-based guideline were identified regarding decreased dosing of bacillus Calmette-Guérin for the treatment of adult patients with bladder cancer. No evidence-based guidelines were identified regarding the reconstitution of bacillus Calmette-Guérin.