Direct Acting Oral Anti-Coagulants for Venous Thromboembolism Prophylaxis after Partial Hip Replacement: Clinical Evidence and Guidelines

Question

1. What is the clinical evidence regarding the use of direct-acting anticoagulants for venous thromboembolism prophylaxis following partial hip replacement?
2. What is the clinical evidence regarding the use of direct-acting anticoagulants for venous thromboembolism prophylaxis following hip fracture repair?
3. What are the evidence-based guidelines regarding the use of direct-acting anticoagulants for venous thromboembolism prophylaxis following partial hip replacement or hip fracture repair?

Key Message

One systematic review with meta-analysis, three randomized controlled trials, and one non-randomized studies were identified regarding direct-acting oral anti-coagulants for venous thromboembolism prophylaxis after partial hip replacement.