Direct Observational Therapy for the Treatment of Tuberculosis: Clinical Evidence and Guidelines

Details

Files
Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1475-000

Question

  1. What is the clinical evidence regarding the provision of direct observational therapy for the treatment of tuberculosis?
  2. What are the evidence-based guidelines regarding the use of direct observational therapy for the treatment of tuberculosis?

Key Message

Eight systematic reviews (seven with meta-analyses), five randomized controlled trials and eight non-randomized studies were identified regarding the provision of direct observation therapy for treatment of tuberculosis. Additionally, eight evidence-based guidelines were identified regarding the use of direct observational therapy for the treatment of tuberculosis.