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Discontinuation Strategies for Patients With Long-Term Z-drug Use: Clinical Evidence and Guidelines

Last updated: January 26, 2015
Project Number: RA0727-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report


  1. What is the clinical evidence regarding strategies to safely and effectively discontinue adult patients from long-term z-drug use?
  2. What are the evidence-based guidelines regarding discontinuation of long-term z-drug use?

Key Message

One randomized controlled trial and three non-randomized studies were identified regarding discontinuation strategies for patients with z-drug use.