Drug-Coated Balloon Angioplasty for the Treatment of Femoropopliteal Peripheral Arterial Disease

Details

Project Status:
Cancelled
Project Line:
Health Technology Review
Project Number:
HT0027-000

Peripheral arterial disease (PAD) is a build-up of plaque in the arteries that causes narrowing or blocking of the blood supply to a person’s organs and limbs. PAD most commonly affects the superficial femoral artery that provides blood supply to the legs. The most common symptom of PAD is muscle leg pain that can often be managed with medication or lifestyle changes. For some people, medical and lifestyle treatment is ineffective or their condition progresses to persistent pain that may be a sign that the limb is at risk of amputation. For these people balloon angioplasty (inserting a catheter into the blocked artery and inflating a small balloon to restore blood flow) may be an effective treatment option. Newer, drug-coated balloons are available and may help overcome the limitations of standard balloon angioplasty.

CADTH, in collaboration with Health Quality Ontario, is conducting a Health Technology Assessment project on the use of drug-coated balloon angioplasty for the treatment of patients with femoropopliteal PAD. Health Quality Ontario will complete a systematic review of clinical evidence, an economic evaluation, and direct patient engagement for patient preferences and values. CADTH is providing input and support though the pan-Canadian HTA Collaborative’s distributed HTA funding model.