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Electronic Cigarettes for the Reduction or Cessation of Smoking: Clinical Utility, Safety, and Guidelines

Last updated: September 5, 2017
Project Number: RB1130-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical evidence regarding the utility of electronic cigarettes for the reduction or cessation of smoking?
  2. What is the clinical evidence regarding the safety associated with electronic cigarettes or other vaping devices?
  3. What is the clinical evidence regarding the safety of propylene glycol, glycerin or polyethylene glycol inhalation from electronic cigarettes or other vaping devices?
  4. What is the clinical evidence regarding the safety of nicotine inhalation from electronic cigarettes or other vaping devices?
  5. What are the evidence-based guidelines regarding the use of electronic cigarettes for the reduction or cessation of smoking?

Key Message

One health technology assessment, 14 systematic reviews, and eight randomized controlled trials were identified regarding electronic cigarettes for the reduction or cessation of smoking or regarding the safety of e-cigarettes. Additionally, three evidence-based guidelines were identified.