Here you’ll find our best evidence on opioids, divided under the topics of Pain Treatment; Misuse, Overdose, and Harms; Opioid Use Disorder (Addiction); and Alternatives to Opioids. We update our Opioid Evidence Bundle regularly with more evidence, including rapid evidence reviews (Rapid Response reports), Environmental Scans, Horizon Scans, and our larger Optimal Use projects with expert recommendations.

Under CADTH’s “Tools and Resources,” you’ll find tools you can use to translate research into action as well as other, non-CADTH information from Choosing Wisely Canada and the Canadian Centre on Substance Use and Addiction.

We’ve selected the following materials to get you started:

Alternatives to Opioids
Misuse/Abuse, Overdose, Harms
Opioid Use Disorder/Addiction Treatment
Pain Treatment
Tools and Resources
Other Reports