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Free T3 or T4 Levels for Hypothyroidism: Clinical Effectiveness and Guidelines

Last updated: May 21, 2015
Project Number: RB0847-000
Product Line: Rapid Response
Research Type: Other Diagnostics
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of assessing free T4 or T3 levels to screen for hypothyroidism?
  2. What is the clinical effectiveness of assessing free T4 or T3 levels to monitor and adjust levothyroxine dose?
  3. What are the evidence-based guidelines regarding the assessment of free T4 or T3 levels to screen for hypothyroidism?

Key Message

Three non-randomized studies and nine evidence-based guidelines were identified regarding the use of free T3 and T4 in the screening and treatment of hypothyroidism.