Linaclotide for Constipation: Clinical and Cost-Effectiveness


( Last Updated : June 21, 2016)
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA0852-000

Details


Question


  1. What is the clinical effectiveness of linaclotide for the treatment of patients with chronic idiopathic constipation?

  2. What is the clinical effectiveness of linaclotide for the treatment of patients with irritable bowel syndrome with constipation?

  3. What is the cost-effectiveness of linaclotide for the treatment of patients with chronic idiopathic constipation

  4. What is the cost-effectiveness of linaclotide for the treatment of patients with irritable bowel syndrome with constipation?


Key Message

Eight systematic reviews, three randomized controlled trials, six non-randomized studies, and three economic evaluations were identified regarding the clinical and cost-effectiveness of linaclotide for the treatment of patients with chronic idiopathic constipation or irritable bowel syndrome with constipation.