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Intranasal versus Intravenous Naloxone for Opioid Overdose in the Pre-Hospital Setting: Comparative Clinical Effectiveness

Last updated: June 10, 2014
Project Number: RB0692-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the comparative clinical effectiveness of intranasal (IN) versus intravenous (IV) naloxone for the treatment of suspected or apparent opioid overdose in the pre-hospital setting?

Key Message

Two non-randomized studies regarding the comparative clinical effectiveness of IN versus IV naloxone for the treatment of suspected or apparent opioid overdose in the pre-hospital setting were identified.