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Last Updated: December 24, 2020
Result type: Reports
Project Number: SR0668-000
Product Line: Reimbursement Review

Generic Name: liraglutide

Brand Name: Saxenda

Manufacturer: Novo Nordisk Canada Inc.

Therapeutic Area: Chronic weight management in adults

Indications: Saxenda® (liraglutide) is indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of: ≥30 kg/m2 or greater (obese), or ≥27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity (e.g., hypertension, type 2 diabetes, or dyslipidemia) and who have failed a previous weight management intervention.

Manufacturer Requested Reimbursement Criteria1: An adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients who have been diagnosed with: Obesity (BMI ≥30 kg/m2) AND prediabetes, or Overweight (BMI ≥27 kg/m2 and ≥30 kg/m2) with one or more weight-related comorbidity AND prediabetes.

Submission Type: Initial

NOC Status at Filing: Post NOC

Project Status: Active

Companion Diagnostics: No

Fee Schedule: Schedule A

  1. The requested reimbursement criteria are provided by the applicant and do not necessarily reflect the views of CADTH. Reimbursement criteria from CADTH will be documented in the final recommendation, if applicable.

Key Milestones2

Call for patient/clinician input open November 26, 2020
Call for patient/clinician input closed January 22, 2021

- Patient input submission received from Diabetes Canada, Gastrointestinal Society and Obesity Canada

Submission received December 23, 2020
Submission accepted January 14, 2021
Review initiated January 15, 2021
Draft CADTH review report(s) provided to sponsor for comment April 09, 2021
Deadline for sponsors comments April 20, 2021
CADTH responses on draft review report(s) provided to sponsor May 07, 2021
Expert committee meeting (initial) May 19, 2021
Draft recommendation issued to sponsor June 01, 2021
June 03, 2021
Draft recommendation posted for stakeholder feedback -