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Long-Term Use of Benzodiazepines: Clinical Effectiveness and Safety

Last updated: July 6, 2015
Project Number: RA0782-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report


  1. What is the clinical effectiveness of long-term versus short-term use of benzodiazepines?
  2. What is the clinical evidence regarding the safety of long-term use of benzodiazepines?

Key Message

Two systematic reviews, one meta-analysis, and three randomized controlled trials were identified regarding the clinical effectiveness and safety of the long-term use of benzodiazepines.