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N-Acetylcysteine Instillation During Bronchoscopy for Patients Requiring Non-Cystic Fibrosis-Related Mucus Secretion Clearance: A Review of Clinical Effectiveness and Guidelines

Last updated: August 2, 2019
Project Number: RC1158-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary with Critical Appraisal
Result type: Report

Question

  1. What is comparative clinical effectiveness of N-acetylcysteine instillation versus saline (normal or hypertonic) during bronchoscopy for non-cystic fibrosis patients requiring mucus secretion clearance?
  2. What are the evidence-based guidelines for N-acetylcysteine instillation during bronchoscopy for non-cystic fibrosis patients requiring mucus secretion clearance?

Key Message

No relevant literature was identified regarding the comparative clinical effectiveness of N-acetylcysteine instillation versus saline (normal or hypertonic) during bronchoscopy for non-cystic fibrosis patients requiring mucus secretion clearance. Additionally, no evidence-based guidelines were identified regarding N-acetylcysteine instillation during bronchoscopy for non-cystic fibrosis patients requiring mucus secretion clearance.