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Naltrexone for Alcohol Addiction: Clinical Effectiveness, Cost Effectiveness, and Guidelines

Last updated: June 10, 2019
Project Number: RB1350-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of injectable extended-release naltrexone for the treatment of alcohol dependency disorder?
  2. What is the cost effectiveness of injectable extended-release naltrexone for the treatment of alcohol dependency disorder?
  3. What are the evidence-based guidelines regarding the use of injectable extended-release naltrexone for the treatment of alcohol dependency disorder?

Key Message

One systematic review with a meta-analysis, four randomized controlled trials, two non-randomized studies, and one evidence-based guideline were identified regarding the clinical effectiveness of naltrexone for alcohol addiction. No relevant economic evaluations were identified.