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Naltrexone for Alcohol Dependence: Clinical Effectiveness

Last updated: January 3, 2017
Project Number: RA0882-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report

Question

  1. What is the clinical effectiveness of naltrexone for the treatment of alcohol dependence?
  2. What is the clinical effectiveness of naltrexone for the treatment of alcohol dependence in individuals with co-dependencies?
  3. What is the clinical effectiveness of naltrexone in combination with acamprosate for the treatment of alcohol dependence?
  4. What is the cost-effectiveness of naltrexone for the treatment of alcohol dependence?

Key Message

One health technology assessment, nine systematic reviews and meta-analyses, 13 randomized controlled trials, and three economic evaluations were identified regarding naltrexone for the treatment of alcohol dependence.