New at CADTH — October 2019

News and Events

Dr. Brian O’Rourke has announced his intention to retire from CADTH, effective March 31, 2020. Dr. O’Rourke joined CADTH in January 2009 after a distinguished career as a pharmacist and health care executive with the Canadian military. Under his leadership, CADTH has grown significantly and is recognized internationally as one of the pre-eminent health technology assessment agencies in the world. Brian leaves a tremendous legacy at CADTH in many areas. Everyone at CADTH is incredibly grateful for his hard work and unwavering commitment. Congratulations Dr. O’Rourke on a job well done and a retirement well deserved. Learn more here.

CADTH is pleased to announce the 2020 CADTH Symposium Travel Award Program for students and patient group representatives. This year, eligible students and patient group representatives can receive up to $2,000 to offset registration, travel, food, accommodation, and other conference-related expenses. More details on this opportunity here.

CADTH is looking for volunteers to review abstracts submitted for presentation at the 2020 CADTH Symposium. This is a great way to participate in developing a stellar program that will feature relevant and engaging topics in a wide variety of formats: workshops, oral presentations, poster presentations, panel discussions, debates, and breakfast sessions. If you’re interested in joining the Abstract Review Committee, please register here.

CADTH will be hosting a webinar on November 5th, in collaboration with Continuing Education and Development for Nurses (CEDN), on the current evidence on Internet-delivered cognitive behavioral therapy (iCBT). This webinar will also include information on Saskatchewan’s Online Therapy Unit. Please register here.

Drug Reimbursement Recommendations

CADTH recently issued the following CADTH Canadian Drug Expert Committee (CDEC) drug reimbursement recommendations:

• fluocinolone acetonide intravitreal implant (Iluvien) for diabetic macular edema.

CADTH recently issued the following CADTH pan-Canadian Oncology Drug Review (pCODR) Expert Review Committee (pERC) drug reimbursement recommendations:

• daratumumab in combo with bortezomib, melphalan, and prednisone (Darzalex) for multiple myeloma (newly diagnosed)
• trifluridine-tipiracil (Lonsurf) for gastric cancer. 

CADTH Reports

CADTH recently completed the following reports:

Environmental Scan

• Collaboration in Health Technology Assessment in Canada – Report
• Programs for the Treatment of Opioid Addiction in Canada – Report

Rapid Response Reports — Drug

• Enzyme Replacement Therapy and Eliglustat for Gaucher Disease Type 1: Guidelines – Reference List
• Glatiramer Acetate and Interferon Beta 1a and 1b for Clinically Isolated Syndrome: A Review of Clinical Effectiveness and Guidelines – Summary With Critical Appraisal
• Minocycline for Relapsing-Remitting Multiple Sclerosis and Clinically Isolated Syndrome: A Review of Clinical Effectiveness and Guidelines - Summary With Critical Appraisal
• Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Diabetic Nephropathy: A Review of Clinical Effectiveness – Summary With Critical Appraisal
• Second-Line Therapy for Patients with Relapsing-Remitting Multiple Sclerosis: A Review of Guidelines – Summary With Critical Appraisal

Rapid Response Reports — Medical Devices and Systems

• Radical Prostatectomy and Radiation Therapy for Prostate Cancer: Clinical Effectiveness and Guidelines – Reference List
• Cryotherapy for Prostate Cancer: Clinical Effectiveness and Guidelines – Reference List
• Manual Therapy for Persistent or Chronic Non-Specific Neck Pain: Clinical Effectiveness, Cost-Effectiveness and Guidelines – Reference List
• Dissolution Techniques for Buprenorphine and Buprenorphine-Naloxone: Clinical Effectiveness and Guidelines – Reference List
• Transfer Belts for Position Changes in Partially Mobile Patients: Safety and Guidelines – Summary of Abstracts
• Point of Care Ultrasound for Assessment of Patients with Obstetrical Issues in Emergency Departments: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Point of Care Ultrasound for Assessment of Patients with Physical Trauma in Emergency Departments: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Positioning of Long-Term Care Patients: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Lateral Rotation Mattresses for the Prevention and Treatment of Pressure Injuries: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Discharge Criteria for Procedural Sedation Patients: Guidelines – Summary of Abstracts
• Hybrid Closed Loop Insulin Delivery Systems: Clinical Effectiveness – Summary of Abstracts
• Flexible Dentures for Edentulism: Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Management of Spinal Cord Injury Patients: Guidelines – Summary of Abstracts
• Communication Strategies and Devices for Patients with Total Locked-in Syndrome: Guidelines – Summary of Abstracts
• Single-Use Holter Monitors in an Outpatient Setting: Clinical Utility, Diagnostic Accuracy - Summary of Abstracts
• Anal Cancer Screening in High-Risk Populations: Clinical Effectiveness, Diagnostic Accuracy, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Sterile Techniques for Patients Undergoing Tracheostomy: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Accelerated Resolution Therapy for Post-Traumatic Stress Disorder, Anxiety Disorders, or Mood Disorders: Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Low-Level Disinfection Techniques and Solutions for Infusion Pump Cleaning: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Orthotic Walking Boots for Patients with Fractures or Ligament Injuries: A Review of Clinical Effectiveness and Cost-Effectiveness – Summary With Critical Appraisal
• Custom-Made Foot Orthoses Versus Prefabricated foot Orthoses: A Review of Clinical Effectiveness and Cost-Effectiveness – Summary With Critical Appraisal
• Pharmacist-Led Interventions for Tobacco Smoking Cessation: A Review of Clinical Effectiveness and Cost-Effectiveness – Summary With Critical Appraisal
• Pharmacist-Led Medication Reviews: A Review of Clinical Utility and Cost-Effectiveness – Summary With Critical Appraisal
• Routine Pathology for Intrauterine Devices and Therapeutic Abortion: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines - Summary With Critical Appraisal
• Cognitive Behavioural Therapy for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness – Summary With Critical Appraisal
• Mindfulness Training and Yoga for the Management of Chronic Non-malignant Pain: A Review of Clinical Effectiveness and Cost-effectiveness – Summary With Critical Appraisal
• Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety and Guidelines – Summary With Critical Appraisal
• Rapid Genome-wide Testing: A Review of Clinical Utility, Cost-Effectiveness, and Guidelines – Summary With Critical Appraisal
• Smartphone-, Tablet-, or App-Based Portable Ultrasound: A Review of Clinical Effectiveness – Summary With Critical Appraisal
• Fecal Occult Blood Testing in Acute Care Settings: A Review of Clinical Utility – Summary With Critical Appraisal
• Transcatheter Aortic Valve Implantation for Aortic Stenosis: A Rapid Qualitative Review – Summary with Critical Appraisal
• Strength-Based Exercise for Chronic Non-Cancer Back Pain: A Review of Clinical Effectiveness – Summary with Critical Appraisal

Other Tools

• In Brief: International Policies on the Appropriate Use of Biosimilar Drugs
• In Brief: Buprenorphine for Opioid Use Disorder
• In Brief: Buprenorphine for Opioid Use Disorders During Pregnancy: A Review
• In Brief: Multidisciplinary Treatment Programs for Patients With Chronic Non-Malignant Pain: An Update of a Review
• In Brief: Evidence HPV Self-Sampling for Primary Cervical Cancer Screening: A Review of Diagnostic Test Accuracy and Clinical Evidence
• In Brief: Mindfulness for Chronic Pain
• Hospital News article: “Stitching Together New Evidence on Triclosan-Coated Sutures for Reducing Surgical Site Infections” 

Tell Us What You Think

We love hearing how our products and services are influencing health care policies, clinical practices, and patient outcomes. If you have a success story to share, please get in touch with your CADTH Liaison Officer.

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