New at CADTH — September 2019

News and Events

CADTH is now accepting abstracts for workshops, panels, debates, breakfast sessions, oral presentations, and posters for the 2020 CADTH Symposium to be held in Toronto April 19 to 21, 2020. The theme is Decision-Making in an Age of Uncertainty. Abstracts must be submitted online at Call for Abstracts.

CADTH is pleased to announce the details of the second of its lecture series this fall entitled, Why Organizations, Researchers, and Patients Are Falling Prey to Predatory Journals taking place on October 10, 2019. Learn more about the lecture’s speaker, Dr. Kelly Cobey, and register here.

CADTH will be hosting a webinar, in collaboration with Continuing Education and Development for Nurses (CEDN), on the current evidence on Internet-delivered cognitive behavioural therapy (iCBT) and hear about Saskatchewan’s Online Therapy Unit. Please register here.

Join CADTH for a webinar on the current evidence on mindfulness and the science behind it for chronic non-cancer pain. Please register here.

Drug Reimbursement Recommendations

CADTH recently issued the following CADTH Canadian Drug Expert Committee (CDEC) drug reimbursement recommendations:

• >Baricitinib (Olumiant) for Rheumatoid Arthritis

CADTH recently issued the following CADTH pan-Canadian Oncology Drug Review (pCODR) Expert Review Committee (pERC) drug reimbursement recommendations:

• Lutetium Lu 177 dotatate (Lutathera) for Gastroenteropancreatic neuroendocrine tumours
• Brigatinib (Alunbrig) for Non-Small Cell Lung Cancer (NSCLC)
• Pembrolizumab (Keytruda) for Melanoma Adjuvant Treatment
• Larotrectinib (Vitrakvi) for Neurotrophic Tyrosine Receptor Kinase (NTRK) Locally Advanced or Metastatic Solid Tumours
• Bosutinib (Bosulif) for Chronic Myeloid Leukemia

CADTH Reports

CADTH recently completed the following reports:

Technology Review

• Ivabradine (Lancora) for Heart Failure

Rapid Response Reports — Drug

• Cancer Immunotherapy After Adjuvant Immunotherapy: Clinical Effectiveness and Guidelines – Reference List
• Sugammadex for the Reversal of Neuromuscular Blockade in Surgical Patients: A Review of Clinical Effectiveness and Cost-Effectiveness – Summary with Critical Appraisal
• Lipid Formulations for Patients Requiring Parenteral Nutrition: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines – An Update – Summary with Critical Appraisal
• Injectable Botulinum Toxin for Pelvic Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary with Critical Appraisal
• Acetylsalicylic Acid for Primary Prevention of Cardiovascular Events: Clinical Effectiveness and Guidelines – Summary of Abstracts
• N-Acetylcysteine Instillation During Bronchoscopy for Patients Requiring Non-Cystic Fibrosis-Related Mucus Secretion Clearance: A Review of Clinical Effectiveness and Guidelines – Summary with Critical Appraisal
• Salbutamol Administration via Nebulizer Versus Metered-Dose Inhalers: Clinical Effectiveness and Cost-Effectiveness – Summary of Abstracts
• Thrombolytics for Patients with Acute or Massive Pulmonary Embolisms: Clinical Effectiveness and Guidelines – Summary of Abstracts
• Duration of Bisphosphonate Treatment for Patients with Osteoporosis: Clinical Evidence and Guidelines – Reference List

Rapid Response Reports — Medical Devices and Systems

• Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines – Reference List
• Interventions for the Treatment and Management of Clostridioides Difficile: Clinical Effectiveness and Guidelines – Reference List
• Interventions for the Diagnosis of Clostridioides Difficile: Clinical Effectiveness and Guidelines – Reference List
• Screening Triage Tools and Management Algorithms for Adult Sepsis Patients: Clinical Utility and Guidelines – Reference List
• Routine Monitoring of Gastric Residual Volume During Enteral Feeding of Adult Inpatients: Clinical Utility and Guidelines – Reference List
• Prostate-Specific Antigen Testing for Prostate Cancer: Clinical Utility and Guidelines – Reference List
• Neuromuscular Electrical Stimulation for Lower Limb Ulcers, Edema, and Thrombosis: Clinical Effectiveness and Cost-Effectiveness – Reference List
• Wearables With Neuroreceptor Activation Patterns for Foot Neuropathy or Musculoskeletal Foot or Back Pain: Clinical Effectiveness – Reference List
• Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Natriuretic Peptide Testing for Monitoring of Oncology Therapy: Clinical Utility, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Natriuretic Peptide Testing for Cardiac Amyloidosis: Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Orthotics Material for Patients Requiring Foot Orthotics: Clinical Effectiveness and Cost Effectiveness – Summary of Abstracts
• Live Virus Vaccination in Hospital, Hospice, Nursing Home, and Long-Term Care Settings: Guidelines – Summary of Abstracts
• Pediatric Palliative Care Assessment Tools in the Home-Care Setting: Guidelines – Summary of Abstracts
• Frequency of Long-Term Indwelling Urinary Catheter Replacement: Clinical Effectiveness and Cost-Effectiveness – Summary of Abstracts
• Medical Follow-up and Discharge of Individuals Receiving Electric Shock or Blunt Trauma From Non-Lethal Weapons: Guidelines – Summary of Abstracts
• Drug-Eluting Stents for Patients with Coronary Artery Disease: Comparative Clinical Effectiveness – Summary of Abstracts
• Balloon Eustachian Tuboplasty for Patients with Eustachian Tube Dysfunction: Clinical Effectiveness – Summary of Abstracts
• Point of Care Ultrasound for Assessment of Patients in Emergency Departments: Guidelines – Summary of Abstracts
• Rapid Genome-Wide Testing: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Overnight Bags for Adults With Long-Term Indwelling Urinary Catheters: Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Bright Light Therapy for Depression: Clinical Effectiveness – Summary of Abstracts
• Point of Care Ultrasound for Assessment of Patients with Suspected or Known Chronic Heart Failure in Emergency Departments: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Point of Care Ultrasound for Assessment of Patients with Deep Vein Thrombosis in Emergency Departments: Clinical Utility and Cost-Effectiveness – Summary of Abstracts
• Orthotic Braces for Idiopathic Scoliosis: Guidelines – Summary of Abstracts
• Telemammography for Breast Cancer Diagnosis: Clinical Utility, Cost-Effectiveness, and Guidelines – Summary of Abstracts
• Pulsed Electron Avalanche Knife (PEAK) PlasmaBlade versus Traditional Electrocautery for Surgery: A Review of Clinical Effectiveness and Cost-Effectiveness – Summary with Critical Appraisal
• Lyophilized Versus Frozen Fecal Microbiota Transplant for Recurrent Clostridium Difficile Infection, Inflammatory Bowel Disease, and Irritable Bowel Syndrome: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary with Critical Appraisal
• Portable Stroke Detection Devices for Patients With Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness – Summary with Critical Appraisal
• Multidisciplinary Medication Review in Long-Term Care: A Review of Clinical Utility, Cost-Effectiveness, and Guidelines – Summary with Critical Appraisal
• Motorized Walking Devices for Patients With Compromised Mobility: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines – Summary with Critical Appraisal
• Natriuretic Peptide Testing for Monitoring of Heart Failure Therapy: A Review of Clinical Effectiveness, Clinical Utility, Cost-Effectiveness, and Guidelines – Summary with Critical Appraisal

Rapid Response Report – Non-Pharma Mental Health Intervention

• Canine and Equine Therapy for Mental Health: A Review of Clinical Effectiveness – Summary with Critical Appraisal

Other Tools

• In Brief: Axicabtagene Ciloleucel for Large B-Cell Lymphoma
• In Brief: Acetylcysteine for Patients Requiring Mucus Secretion Clearance

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