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Nonsteroidal Anti-Inflammatory Drugs and Acute Kidney Injury: Safety

Published on: January 21, 2019
Project Number: RB1299-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the evidence associated with the development of acute kidney injury upon the use of nonsteroidal anti-inflammatory drugs to treat acute pain?

Key Message

Four systematic reviews, one meta-analysis, one randomized controlled trial, and five non-randomized studies were identified regarding the evidence associated with the development of acute kidney injury upon the use of nonsteroidal anti-inflammatory drugs to treat acute pain.

Tags

kidney, pain management, acute kidney injury, acute pain, anti-inflammatory agents, anti-inflammatory agents, non-steroidal, aspirin, butanones, cyclooxygenase 2 inhibitors, dental care, diclofenac, etodolac, ibuprofen, ketoprofen, ketorolac, naproxen, pain, piroxicam, pyrazoles, sulfonamides, toothache, NSAIDs, Nonsteroidal anti-inflammatories, nonsteroidal anti-inflammatory agents, NSAID, nonsteroidal anti-inflammatory drugs, Acute kidney failure, acute kidney injury, Acute pain, cox-2 inhibitor, dental pain, AKI