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Oral Polysaccharide Iron Complex and Heme Iron Polypeptide for Those Requiring Iron Supplementation: Clinical Effectiveness, Cost-Effectiveness, Safety, and Guidelines

Last updated: February 26, 2019
Project Number: RA1014-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report

Question

  1. What is the comparative clinical effectiveness of oral polysaccharide iron complex or heme iron polypeptide versus oral iron salts for iron supplementation?
  2. What is the comparative clinical effectiveness of oral polysaccharide iron complex or heme iron polypeptide versus injectable iron supplements for iron supplementation?
  3. What is the clinical evidence regarding the safety of oral polysaccharide iron complex or heme iron polypeptide versus injectable iron supplements for iron supplementation?
  4. What is the cost-effectiveness of oral polysaccharide iron complex or heme iron polypeptide for iron supplementation?
  5. What are the evidence-based guidelines regarding the use of oral polysaccharide iron complex or heme iron polypeptide for iron supplementation?

Key Message

Two randomized controlled trials were identified on the clinical effectiveness of oral polysaccharide iron complex and heme iron polypeptide for those requiring iron supplementation. No relevant economic evaluations or evidence-based guidelines were identified.