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Pasteurized Donor Milk versus Formula for Preterm Infants: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Last updated: November 2, 2020
Project Number: RA1145-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Reference List
Result type: Report

Question

  1. What is the comparative clinical effectiveness of pasteurized donor milk compared with formula for preterm babies of gestational age 34 weeks or earlier?
  2. What is the comparative cost-effectiveness of pasteurized donor milk compared with formula for preterm babies of gestational age 34 weeks or earlier?
  3. What are the evidence-based guidelines regarding the use of donor milk or formula for preterm babies of gestational age 32 to 34 weeks?

Key Message

One systematic review and one randomized controlled trial were identified regarding the comparative clinical effectiveness of pasteurized donor milk compared with formula for preterm babies of gestational age 34 weeks or earlier. No relevant literature was identified regarding the comparative cost-effectiveness of pasteurized donor milk compared with formula for preterm babies of gestational age 34 weeks or earlier. In addition, no relevant evidence-based guidelines were identified regarding the use of donor milk or formula for preterm babies of gestational age 32 to 34 weeks.