- What are the evidence-based guidelines for the pharmacologic management of ADHD in children, adolescents, and adults?
Stimulant drugs are the first-choice pharmacological treatment for ADHD in children, adolescents, and adults. Atomoxetine is the preferred initial choice of treatment when there is a risk that stimulant drugs may be abused/misused or diverted. Atomoxetine is also the recommended drug of choice when stimulant ADHD drugs are contra-indicated, ineffective, or poorly tolerated. There is limited evidence to support the efficacy or safety of combination therapy for ADHD comprising stimulant and non-stimulant drugs in patients with inadequate clinical response to monotherapy.