Report in Brief
- What is the clinical effectiveness of the point of care testing (POCT) technologies to assess white blood cell counts (WBC) and differentials when compared to clinical laboratory test methods?
- What is the diagnostic accuracy and precision of the POCT technologies to assess WBC counts and differentials when compared to clinical laboratory testing methods?
- What is the cost-effectiveness of using PCOT to assess WBC counts and differentials when compared to clinical laboratory testing methods?
- What are the guidelines associated with the use of POCT to asses WBC counts and differentials?
In general, POC testing is reliable and produces comparable results to a standard reference analyzer. The HemoCue WBC analyzer was also found to be stable under different conditions, and the counts can be interfered by a number of pathologic conditions. A guideline from the International Council for Standardization in Hematology (ICSH) was developed in 2008 to provide information on how to develop and manage a POC service so that reliable hematology results are produced. There were no studies on comparative clinical effectiveness, and cost effectiveness between POC WBC testing and standard laboratory testing.