Begin main content

Point-of-care versus Central Laboratory Troponin Testing for Diagnosis of Acute Coronary Syndrome in Acute Care Settings: A Review of the Clinical and Economic Evidence

Published on: October 18, 2012
Project Number: RC0396-000
Product Line: Rapid Response
Report Type: Summary with Critical Appraisal
Result type: Report

Question

1. For patients with suspected acute coronary syndrome (ACS) in acute care settings, what is the diagnostic test performance of:

  • central laboratory troponin T compared with point-of-care troponin T assays?
  • central laboratory troponin I compared with point-of-care troponin I assays?

 

2. For patients with suspected ACS in acute care settings, what is the comparative clinical effectiveness of:

  • central laboratory troponin T compared with point-of-care troponin T assays?
  • central laboratory troponin I compared with point-of-care troponin I assays?

 

3. For patients with suspected ACS in acute care settings, what is the cost-effectiveness of:

  • central laboratory troponin T compared with point-of-care troponin T assays?
  • central laboratory troponin I compared with point-of-care troponin I assays?

Key Message

POC troponin I testing decreased the length of stay in the emergency department compared to central laboratory troponin I testing. Central laboratory troponin testing was found have better diagnostic accuracy than conventional POC troponin assays. However, POC troponin assay results correlated well with the results of central laboratory troponin assays.

Tags

clinical laboratory techniques, laboratories, point-of-care systems, tnt, acute coronary syndrome, hospital laboratories, troponin, laboratory tests, point of care, Hospital, Troponin Tni, cTnI, cTnT, cTn, POC, POCT, Central