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Positive Airway Pressure and Oral Appliances for the Treatment of Obstructive Sleep Apnea in Adults

Last updated: April 5, 2021
Project Number: RB1563-000
Product Line: Rapid Response
Research Type: Medical Device
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of bilevel or continuous positive airway pressure devices or oral appliances for the treatment of obstructive sleep apnea in adults?
  2. What is the comparative clinical effectiveness of bilevel or continuous positive airway pressure devices versus oral appliances for the treatment of obstructive sleep apnea in adults?
  3. What is the cost-effectiveness of bilevel or continuous positive airway pressure devices or oral appliances for the treatment of obstructive sleep apnea in adults?

Key Message

Fifteen systematic reviews (10 with meta-analysis) and 26 randomized controlled trials were identified regarding the clinical effectiveness of bilevel or continuous positive airway pressure devices or oral appliances for the treatment of obstructive sleep apnea in adults. Three systematic reviews (2 with meta-analysis) and 7 randomized controlled trials were identified regarding the comparative clinical effectiveness of bilevel or continuous positive airway pressure devices versus oral appliances treatment for the treatment of obstructive sleep apnea in adults. No economic evaluations were identified regarding the cost-effectiveness of bilevel or continuous positive airway pressure devices or oral appliances for the treatment of obstructive sleep apnea in adults.