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Liquid-based cytology and human papillomavirus testing in cervical cancer screening

Last Updated: November 17, 2003
Result type: Reports

Technology Name Tests for the human papillomavirus (HPV) Liquid-based cytology (LBC) Disease/Condition Cervical cancer is mainly caused by the sexually transmitted human papillomavirus (HPV). Among high grade precancerous lesions, 75% to 95% test positive for HPV infection. In 2003, an estimated 1,400 women in Canada will develop invasive...

A clinical and economic review of stroke rehabilitation services

Last Updated: August 27, 2003
Result type: Reports

Technology Name Stroke rehabilitation services and programs Disease/Condition There are over 40,000 strokes each year and stroke is the fourth leading cause of mortality in Canada. Death and disability from stroke costs the Canadian economy approximately $2.7 billion per year. Technology Description Stroke rehabilitation offers the opportun...

Major Depressive Disorder – Focused Critical Appraisal of a Network Meta-Analysis

Last Updated: February 18, 2020
Result type: Reports
Product Line: Technology Review
Research Type: Drug

Major depressive disorder (MDD) is a common, debilitating, and recurrent mental health disorder. Over the past decades, multiple classes of antidepressant drugs have been developed to treat this condition. The relative effectiveness and safety of antidepressants are uncertain. This project will review a recently published network meta-analysis f...

  • Project Number: HE0022-000

caplacizumab (Cablivi)

Last Updated: March 12, 2020
Result type: Reports
Product Line: Common Drug Review
Generic Name: caplacizumab
Indications: Acquired thrombotic thrombocytopenic purpura (aTTP)

  • Brand Name: Cablivi
  • Manufacturer: Sanofi-Genzyme, a division of sanofi-aventis Canada Inc.
  • Project Number: SR0633-000
  • Project Status: Active
  • Submission Type: New

Newborn Screening for Medium Chain Acyl CoA Dehydrogenase Deficiency Using Tandem Mass Spectrometry: Clinical and Cost-effectiveness.

Last Updated: March 10, 2006
Result type: Reports

Technology Tandem mass spectrometry (MS/MS)-based newborn screening for medium chain acyl~CoA dehydrogenase deficiency (MCADD). Disease MCADD is an inherited metabolic disorder. In Canada, there are about 20 incident cases/year. Most MCADD patients are asymptomatic before an acute episode, which manifests with signs of encephalopathy, hypogly...

The pCODR Expert Review Committee (pERC)

Published on: February 27, 2019
Result type: General Content

The role of the pan-Canadian Oncology Drug Review (pCODR) Expert Review Committee (pERC) is to assess the clinical evidence and cost-effectiveness of cancer drugs in order to make recommendations to the provinces and territories to help guide their drug funding decisions. A submission for the assessment of a cancer drug may be made by a pharmac...