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Treatment for Opioid Dependence: A Review of Guidelines

Last updated: September 14, 2012
Project Number: RC0390-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Summary with Critical Appraisal
Result type: Report


  1. What are the evidence-based guidelines for the assessment and treatment of opioid dependent patients?
  2. What are the evidence-based guidelines for the detoxification or treatment of opioid dependent pregnant women?

Key Message

Evidence-based guidelines indicate that opioid dependent patients should be assessed with the DSM-IV-TR diagnostic criteria. Methadone maintenance treatment was recommended as a standard treatment for opioid dependence including pregnant opioid-dependent women. Recommendations state that detoxification should be avoided during pregnancy and that buprenorphine/naloxone combination therapy should not be used in pregnant women.