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Treatment for Post-Traumatic Stress Disorder, Operational Stress Injury, or Critical Incident Stress: A Review of Guidelines

Last updated: April 27, 2015
Project Number: RC0651-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Summary with Critical Appraisal
Result type: Report

Question

  1. What are the evidence-based guidelines regarding treatment of patients with PTSD?
  2. What are the evidence-based guidelines regarding treatment of patients with operational stress injury?
  3. What are the evidence-based guidelines regarding treatment of patients with critical incident stress?

Key Message

Selective serotonin reuptake inhibitors (SSRIs; fluoxetine, paroxetine and sertraline), and serotonin norepinephrine reuptake inhibitor (SNRI; venlafaxine) are recommended as first-line pharmacological treatment of PTSD, while cognitive behavioral therapy (CBT), stress management therapy, and eye movement desensitization and reprocessing (EMDR) are recommended as psychological approaches for PTSD. There are no guidelines that have specific recommendations for OSI or CIS.