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Vitamin B12 Testing in the General Population: Clinical and Cost-Effectiveness and Guidelines

Last updated: January 21, 2015
Project Number: RB0781-000
Product Line: Rapid Response
Research Type: Other Diagnostics
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of vitamin B12 testing in the general population?
  2. What is the cost-effectiveness of vitamin B12 testing in the general population?
  3. What is the clinical effectiveness of second tier vitamin B12 testing in patients with low vitamin B12 results?
  4. What is the cost-effectiveness of second tier vitamin B12 testing in patients with low vitamin B12 results?
  5. What are the evidence-based guidelines regarding vitamin B12 testing in the general population?

Key Message

One systematic review and one evidence-based guideline were identified regarding the clinical effectiveness of vitamin B12 testing and second tier testing in the general population. No relevant literature was identified regarding the cost-effectiveness of either vitamin B12 testing or second tier vitamin B12 testing.