COVID-19 Update

CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.

Reports

Convalescent Plasma Therapy for the Treatment of COVID-19: A Review of Clinical Effectiveness

• Convalescent plasma (CP) therapy is an intervention whereby plasma is collected from recovered COVID-19 patients in the hope that the disease-specific antibodies could help the recipient recover from COVID-19.
• Evidence on the effectiveness of CP therapy for the treatment of COVID-19 is still in the early stages.
• This report (updated on March 8, 2021) summarizes the current evidence and it is updated regularly as a living review.

Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19

• This report (last updated on March 5, 2021) provides information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19.
• Ongoing trials of vaccines and plasma-based therapies are addressed in separate CADTH reports.

COVID-19 News

Visit our COVID-19 news page to stay on top of all the emerging information we are monitoring and updating. Here’s the latest news:

• WHO Solidarity Study: Remdesivir
  CADTH assessed 5 randomized controlled trials, including the interim study results from the WHO Solidarity trial, in a health technology review on remdesivir.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:

• Pan-Canadian Health Organizations
• Federal, Provincial, and Territorial Information

CAN’T FIND WHAT YOU NEED? LET US KNOW

Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.

The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal.