COVID-19 Update

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CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.

Reports

Chloroquine or Hydroxychloroquine to Prevent or Treat COVID-19

  • This report (last updated on April 23, 2021) reviews the current scientific evidence on the potential benefits and harms of chloroquine and hydroxychloroquine for the prevention or treatment of COVID-19.
  • The current evidence does not support the use of high-dose chloroquine because of concerns of cardiac toxicity and increased lethality relative to low-dose chloroquine.
  • The results of the included studies also do not support the use of hydroxychloroquine for treating patients with mild, moderate, or severe COVID-19, nor does hydroxychloroquine appear to prevent COVID-19 post-exposure.

COVID-19 News

Visit our COVID-19 news page to stay on top of all the emerging information we are monitoring and updating.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:

  • Pan-Canadian Health Organizations
  • Federal, Provincial, and Territorial Information

CAN’T FIND WHAT YOU NEED? LET US KNOW

Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.

The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal.