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Duration of Bisphosphonate Treatment for Patients with Osteoporosis: Clinical Evidence and Guidelines

Last updated: August 22, 2019
Project Number: RA1059-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report

Question

  1. What is the clinical evidence for varying treatment duration and courses of bisphosphonates for osteoporosis?
  2. What are the evidence-based guidelines regarding length of treatment with bisphosphonates for osteoporosis?

Key Message

One health technology assessment, six systematic reviews (one with meta-analyses), three randomized controlled trials, and five non-randomized studies were identified regarding the clinical evidence for varying treatment duration and courses of bisphosphonates for osteoporosis. Six evidence-based guidelines were identified regarding the length of treatment with bisphosphonates for osteoporosis.