Reimbursement Review Reports

The latest CADTH Reimbursement Review reports are posted to this page. CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

Brand Name Generic Name Therapeutic Area Sort ascending Recommendation Type Project Status Date Submission Received Date Recommendation Issued
Trikafta elexacaftor / tezacaftor / ivacaftor and ivacaftor Cystic fibrosis, F508del CFTR mutation Reimburse with clinical criteria and/or conditions Complete
Orkambi lumacaftor/ivacaftor Cystic Fibrosis, F508del CFTR mutation Do not reimburse Complete
Cayston Aztreonam for inhalation solution Cystic fibrosis, chronic pulmonary pseudomonas aeruginosa infections List with clinical criteria and/or conditions Complete
Kalydeco Ivacaftor Cystic Fibrosis, CFTR gating mutations List with criteria/condition Complete
Quinsair Levofloxacin Cystic fibrosis with chronic pulmonary Pseudomonas aeruginosa infections Reimburse with clinical criteria and/or conditions Complete
Zolinza vorinostat Cutaneous T-cell lymphoma CADTH is unable to recommend reimbursement as a submission was not filed by the manufacturer Not filed
Signifor Pasireotide diaspartate Cushing’s disease Do not list Complete
Ilaris Canakinumab Cryopyrin-Associated Periodic Syndrome Do not list Complete
Rinvoq upadacitinib Crohns disease Reimburse with clinical criteria and/or conditions Complete
Inflectra (Subsequent Entry Biologic) Infliximab Crohn’s disease and Ulcerative Colitis Reimburse with clinical criteria and/or conditions Complete