Reimbursement Review Reports

The latest Reimbursement Review reports are posted to this page. Our Reimbursement Reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

Brand Name Sort descending Generic Name Therapeutic Area Recommendation Type Project Status Date Submission Received Date Recommendation Issued
Opdivo nivolumab Resectable Non-Small Cell Lung Cancer Reimburse with clinical criteria and/or conditions Complete
Opdivo & Yervoy in combo Nivolumab & Ipilimumab in combo Metastatic Melanoma Reimburse with clinical criteria and/or conditions Complete
Opdivo in combination with Yervoy Nivolumab in combination with Ipilimumab NSCLC Reimburse with clinical criteria and/or conditions Complete
Opdivo in combination with Yervoy Nivolumab in combination with Ipilimumab Advanced or Metastatic Renal Cell Carcinoma (RCC). Reimburse with clinical criteria and/or conditions Complete
Opdivo-Yervoy nivolumab-ipilimumab Malignant Pleural Mesothelioma (MPM) Reimburse with clinical criteria and/or conditions Complete
Opdualag nivolumab and relatlimab unresectable or metastatic melanoma Reimburse with clinical criteria and/or conditions Complete
Opsumit Macitentan Pulmonary arterial hypertension List with clinical criteria and/or conditions Complete
Opsynvi macitentan and tadalafil Pulmonary arterial hypertension Reimburse with clinical criteria and/or conditions Complete
Oralair Grass Pollen Allergen Extract Allergic rhinitis List with criteria/condition Complete
Orencia Abatacept Arthritis, rheumatoid List with clinical criteria and/or conditions Complete
Orencia Abatacept Arthritis, Rheumatoid List with clinical criteria and/or conditions Complete
Orencia Abatacept Arthritis, Juvenile Idiopathic & Juvenile Rheumatoid List with clinical criteria and/or conditions Complete
Orencia Abatacept Arthritis, Rheumatoid List in a similar manner Complete
Orfadin nitisinone Hereditary tyrosinemia type 1 Reimburse with clinical criteria and/or conditions Complete
Orgovyx relugolix Advanced prostate cancer Active
Orilissa elagolix CADTH is unable to recommend reimbursement as a submission was not filed by the manufacturer Not filed
Orkambi lumacaftor/ivacaftor Cystic Fibrosis, F508del CFTR mutation Do not reimburse Complete
Orkambi lumacaftor/ivacaftor Cystic Fibrosis, F508del CFTR mutation in patients 6 years and older Do not reimburse Complete
Orladeyo berotralstat hereditary angioedema (HAE) Reimburse with clinical criteria and/or conditions Complete
Osphena ospemifene Dyspareunia, vaginal dryness Reimburse with clinical criteria and/or conditions Complete
Otezla Apremilast Arthritis, psoriatic List with criteria/condition Complete
Otezla Apremilast Psoriasis, moderate to severe plaque Reimburse with clinical criteria and/or conditions Complete
Otezla Apremilast Plaque psoriasis Do not list Complete
Oxervate cenegermin Neurotrophic keratitis Reimburse with clinical criteria and/or conditions Complete
Oxlumo lumasiran Primary hyperoxaluria type 1 Reimburse with clinical criteria and/or conditions Complete