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brolucizumab

Last Updated: May 25, 2020
Result type: Reports
Project Number: SR0632-000
Product Line: Common Drug Review

Generic Name: brolucizumab

Brand Name: Beovu

Manufacturer: Novartis Pharmaceuticals Canada Inc.

Indications: Macular degeneration, age-related

Manufacturer Requested Reimbursement Criteria1: For the treatment of neovascular (wet) age-related macular degeneration.

Submission Type: New

Project Status: Active

Companion Diagnostics: No

Date Recommendation Issued: May 21, 2020

Recommendation Type: Reimburse with clinical criteria and/or conditions

Fee Schedule: Schedule A

  1. The requested reimbursement criteria are provided by the applicant and do not necessarily reflect the views of CADTH. Reimbursement criteria from CADTH will be documented in the final recommendation, if applicable.

Key Milestones2

Call for patient input postedAugust 28, 2019
Patient group input closedOctober 18, 2019
Clarification:

- Patient input submission received from Canadian Council of the Blind, CNIB Foundation, Fighting Blindness Canada, Vision Loss Rehabilitation Canada (Joint Submission)

Patient input summary sent for review to patient input groupsDecember 04, 2019
Patient group comments on input summary closedDecember 11, 2019
Clarification:

- No patient input summary feedback received

Submission receivedSeptember 26, 2019
Submission acceptedNovember 28, 2019
Clarification:

- Submission was not accepted for review on 10-Oct-2019

- Revised category 1 requirements received on 25-Nov-2019

Review initiatedNovember 29, 2019
Draft CADTH review report(s) sent to sponsorFebruary 20, 2020
Comments from sponsor on draft CADTH review report(s) receivedMarch 02, 2020
CADTH review team's comments on draft CADTH review report(s) sent to sponsorApril 02, 2020
Canadian Drug Expert Committee (CDEC) meetingApril 15, 2020
CDEC recommendation sent to sponsor and drug plansApril 29, 2020
Embargo period endedMay 13, 2020
CDEC Final Recommendation & CADTH review report(s) issued to sponsor and drug plansMay 21, 2020
CDEC Final Recommendation postedMay 25, 2020
Redaction requests from sponsor on draft CADTH review report(s) receivedJune 04, 2020
Redacted CADTH review report(s) sent to sponsor and drug plans-
Validation of redacted CADTH review report(s) received-
Final CADTH review report(s) posted-