Concurrent Treatment for Substance Use Disorder and Trauma-Related Comorbidities: 2021 Update


( Last Updated : March 31, 2021)
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1171-000

Details


Question


  1. What is clinical effectiveness of concurrent treatment for patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression?

  2. What is the clinical effectiveness of the treatment of 1 condition for the improvement of all symptoms in patients with substance use disorder and comorbid post-traumatic stress disorder, anxiety, or depression?

  3. What are the evidence-based guidelines regarding the treatment of patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression?


Key Message

Two systematic reviews and 8 randomized controlled trials were identified regarding the clinical effectiveness of concurrent treatment for patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression. One systematic review and 2 non-randomized studies were identified regarding the clinical effectiveness of the treatment of 1 condition for the improvement of all symptoms in patients with substance use disorder and comorbid post-traumatic stress disorder, anxiety, or depression. Four evidence-based guidelines were identified regarding the treatment of patients with substance use disorders and comorbid post-traumatic stress disorder, anxiety, or depression.