Manufacturer Requested Reimbursement Criteria1:
As an adjunct to diet and maximally tolerated statin (MTS) therapy, with or without other lipidlowering therapies (LLT), in adult patients with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD), who require additional lowering of LDLC.
Leqvio is indicated as an adjunct to lifestyle changes, including diet, to further reduce low‐density lipoprotein cholesterol (LDL‐C) level in adults with the following conditions who are on maximally
tolerated dose of a statin, with or without other LDL‐C ‐lowering therapies:
Heterozygous familial hypercholesterolemia (HeFH), or
Non‐familial hypercholesterolemia with atherosclerotic cardiovascular disease
The effect of Leqvio on cardiovascular morbidity and mortality has not been determined.